Information about periodic fever syndrome

Information about periodic fever syndrome

The term periodic fever syndromes refers to disorders that cause episodic or possibly periodic fever that are not the result of a viral or bacterial infection. The most widespread form of periodic fever syndrome is called familial Mediterranean fever. This short post will cover information about this rare condition, eg, the affected society, causes, heredity, treatment methods, possible adverse reactions, analysis, and key indications.

FMF disease is inherited by a pair of mutated genes, each received from the father and mother, also known as carriers. Even if the boy or girl suffers from this disease, neither the mother nor the father will automatically show any signs or symptoms of this disease. Someone in the family typically has the disease, and the chance is quite high that another child, whose parents are carriers, could contract familial Mediterranean fever.

Exactly who is most affected by FMF?
So which culture is most often affected by this disorder? Usually, people who are often children suffer from fever accompanied by periods or repeated body shocks including chest, tummy and even joint pain along with swollen joints. This disease is not at all contagious having said that it affects people of Mediterranean and Middle Eastern descent. In general, Jews, Armenians, Turks, and Arabs tend to develop this specific disorder, and even Italians and Greeks tend to be affected infrequently.

The reason behind FMF
There is a possibility that you are wondering, the cause of such a rare dysfunction? Familial Mediterranean fever is simply a genetically inherited autosomal recessive disease, resulting from a MEFV gene. Nicknamed after the Mediterranean Sea, this gene affects a protein called pyrin, which controls the inflammatory reaction in your body. If the defect exists in the gene, the regularity of inflammation is inhibited, leading to recurrence of fever and other episodic attacks and signs, especially amyloidosis. Amyloidosis is the accumulation associated with amyloid proteins that settle in various organs such as the renal system, cardiovascular system, and digestive tract. This, in turn, could lead to more life-threatening disorders, particularly kidney failure. Mental stress, trauma, and infection can trigger these various symptoms, and they typically begin in sufferers before the age of 20.

Periodic fever syndromes tend to be passed from parent to child and are therefore the result of a genetic deficiency or mutation. The MEFV gene is responsible for familial Mediterranean fever, but periodic fever syndromes have different remedies. Since it is unusual to have this type of gene, many people are unaware of this type of deficiency, so it is not surprising that it is important to learn about these types of circumstances.

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